Semaglutide is a modified molecule our bodies make, called GLP-1 analog. It works by increasing insulin production and lowering glucagon secretion as well as targeting areas in the brain that regulate appetite and food intake. A small change in the molecule allows the drug to last weeks in our bodies rather than the natural version our bodies make, which lasts minutes. Originally used for diabetes and sold under the name Ozempic®. In June 2021, Semaglutide was FDA-approved for weight loss.

Semaglutide acts in the following ways:

• Delays how quickly our stomachs digest food. Leading to a feeling of fullness and satisfaction with smaller meal sizes
• Slows intestinal motility so you will feel fuller longer after meals
• Lowers blood sugars, in part by reducing the production of sugar in the liver
• Stimulates insulin secretion by the pancreas